L-Carnitine

L-carnitine is a natural product that participates in the metabolism of our body and has an amino acid nature. It is conditionally irreplaceable and a part of our needs for it are provided by our own body. We get the other part with food or in case of increased needs - as a nutritional supplement to our diet.

We offer you the salt of L-carnitine and tartaric acid - L-carnitine tartrate in an easy-to-digest capsule version. Adding it to your regimen can bring you a variety of health benefits due to the substance's broad action. Athletes will feel its benefits during training as well.

Product Content

• Content in one capsule/dose: 500 mg L-carnitine tartrate
• Doses in a pack: 60 doses

Other ingredients: gelatin capsule.

We offer pure and natural support for your health:

• 100% active ingredients
• Gluten free
• Lactose free
• No added sugar
• Without preservatives and artificial colors
• Not tested on animals.

Recommended intake

It is desirable to take the L-carnitine supplement on an empty stomach, if possible to combine it with a training regimen. In this case, it is taken on an empty stomach before training.

For non-trainers - to be taken between meals.

Do not exceed more than 4 capsules or 2000 mg per day.

Do not exceed the recommended daily dose. To be stored in a dry and cool place. This product is a food supplement and cannot replace a varied diet.

Keep out of the reach of small children. To be used before the date indicated on the package.

Consult your doctor before taking the product if you suffer from any medical condition.

Method of intake

It is desirable to take the L-carnitine supplement on an empty stomach, if possible to combine it with a training regimen. In this case, it is taken on an empty stomach before training.

For non-trainers - to be taken between meals.

Do not exceed more than 4 capsules or 2000 mg per day.

Do not exceed the recommended daily dose. To be stored in a dry and cool place. This product is a food supplement and cannot replace a varied diet.

Keep out of the reach of small children. To be used before the date indicated on the package.

Consult your doctor before taking the product if you suffer from any medical condition.

Side effects and overdose

L-carnitine is a natural chemical compound and metabolite that the human body can only synthesize. For this reason, its supplemental intake is considered safe to a large extent.

Doses of 2 g/day taken over a long period of time do not pose potential risks of side effects.

Side effects are observed after taking more than 3 grams and most often these are the appearance of reflux, heartburn or diarrheal stools.

In long-term and systemic overdose, however, studies indicate that L-carnitine carries an increased risk of atherosclerotic plaque formation.

Excess l-carnitine is absorbed by the intestinal flora and metabolized to TMAO (trimethylamine-oxide) and gamma-butyrobetaine. These substances are associated with an overall increased risk of developing cardiovascular disease.

The trust of our customers is important to us. Therefore, each product has a registration number issued by the Agency responsible for the control of food and food additives, which verifies its authenticity and quality: T032304434

GMP certificate

GMP certificate - Good Manufacturing Practice - represents the gold standard in the production of nutritional supplements.

VitaOn products are manufactured following strict production processes and strict control at every stage, guaranteeing high quality and safety.

GMP certificates are a kind of proof of our company's dedication to providing you with only first-class premium products.

We prioritize consistency, accuracy and cleanliness, and in doing so offer you peace of mind and trust that we are responsible for.

Who is it suitable for?

L-carnitine is an amino acid that is not involved in building proteins, but performs important functions in our body. Part of it is produced by the body itself, and the rest we get with our food.

People with impaired liver or kidney function need and would benefit from taking carnitine in supplement form.

Another group of people whose intake is more than recommended is the group of vegans - all foods rich in l-carnitine are contained exclusively in foods of animal origin. For this reason, vegans often suffer from L-carnitine deficiency.

People dedicated to sports and chasing high results are the ones who most often resort to taking L-carnitine. It increases sports performance, strength, power endurance and contributes to the good work of the heart muscle.

In general, L-carnitine is a safe product with a broad action and many benefits for the human body.

What is L-carnitine?

L-carnitine is an amino acid derivative that is synthesized endogenously (inside the body) from the amino acids - lysine and methionine. This process takes place in the liver, brain and kidneys, and the largest depots of carnitine in the body are skeletal muscles - over 95%.

L-carnitine is a nutrient that is conditionally indispensable. This means that the body can synthesize certain amounts of this amino acid, and the rest it needs to function properly is obtained through food.

Foods rich in l-carnitine are mainly of animal origin, with red meat and fish being the richest in this substance. The name itself comes from Latin - carnis/caro - and means meat, flesh.

Vegetarians cannot get enough L-carnitine because its content in plant-based foods is negligible. Therefore, supplementation with it in the form of a food supplement is important for them.

Prematurely born children, as well as people with impaired kidney function, also fail to synthesize the necessary amounts of it, which necessitates its additional intake as food supplements.

In order to produce adequate amounts of L-carnitine, it is important that the body has sufficient vitamin C.

Forms of L-carnitine

L-carnitine is the standard biologically active form of carnitine that occurs in nature and is most often used in the composition of nutritional supplements.

Other forms of carnitine are:

• D-carnitine - this is an inactive form of carnitine, which after entering the body leads to depletion of carnitine levels, disturbance in fat metabolism and increased oxidative stress. It shows hepatotoxicity, i.e. damages liver cells.
• N-acetyl-L-carnitine (ALCAR) or acetyl L-carnitine - this is the most active form in relation to brain function. Protects against neurodegenerative conditions.
• Glycyl-Propionyl L-carnitine - studies show that this form is most suitable for peripheral vascular pathologies and high blood pressure. It is also believed to increase nitric oxide synthesis, thus improving organ perfusion.
• L-carnitine-L-tartrate (LCLT) - this is the most used form in the field of dietary supplements. It has a number of beneficial effects and is also very quickly absorbed. It is L-carnitine, L-tartrate that is the form that we have used in our product.

Biosynthesis and metabolism of L-carnitine

As we already understood, our body is able to synthesize certain amounts of carnitine on its own. In humans, the substrate for its synthesis is 6-N-trimethyllysine (TML).

It, in turn, is formed by the methylation of the amino acid Lysine. After a hydroxylation process, TML is converted to hydroxytrimethyllysine (HTML), and this reaction requires the participation of ascorbic acid and iron.

After interaction with the enzyme HTML aldolase, HTML is converted to 4-trimethylamine butanaldehyde (TMABA) and glycine. TMABA undergoes a dehydrogenation process and is converted to gamma-butyrobetaine, which is hydroxylated to L-carnitine, a reaction that requires the presence of zinc and iron.

These complex biochemical processes briefly show the need for proper nutrition and the intake of supplements when we fail to meet our daily needs of micro and macronutrients.

Carnitine participates in the process of transporting fatty acids across the mitochondrial membrane by forming a long-chain ester of acetyl L carnitine.

The proteins required for this transport are carnitine palmitoyl transferase 1 and 2. It also participates in the oxidation-reduction processes of converting acetyl-CoA into CoA and vice versa, accepting or donating an acetyl group.

L-carnitine is involved in the transfer of fatty acids from the cytosol to the mitochondria of the cell, where they undergo further oxidation and are burned for energy production.

This process has three stages and is called the carnitine shuttle.

L-carnitine and its relation to human health

A number of studies have been conducted on the role of L-carnitine in human health. Due to its high prevalence in cellular biochemical processes, its potential qualities are being investigated in various aspects of health.

There is more extensive scientific interest in its action in:

• Alzheimer's and other neurovegetative diseases
• Cardiovascular and peripheral vascular diseases
• Diabetes
• Osteoarthritis
• Infertility
• Weight reduction (l-carnitine for weight loss)
• Its effect on sports performance.

Action of L-carnitine as a regulator of energy processes

The main role of l-carnitine in the body is to transport fatty acids/triglycerides from their depots in the cell plasma to the mitochondria. There they undergo beta oxidation and are broken down into energy in a usable form for our body in the form of adenosine triphosphate.

With excessive caloric intake, when glycogen stores are full and the body does not need energy, excess glucose begins to be transformed through the process of lipogenesis into triglycerides. This leads to inhibiting the action of l-carnitine and stopping the fat breakdown processes.

In practice, this is the explanation that when following a regimen for reducing body weight, even a more massive meal that exceeds the body's current energy needs leads to the cessation of lipolysis.

On the contrary - during long periods of fasting (more than 48 hours) or serious physical exertion, adenosine triphosphate levels decrease significantly. This is a signal for the body to start mobilizing fatty acids from their stores and, with the help of l-carnitine, transport them to the mitochondria, where they can be used for energy.

Benefits of L-carnitine in the treatment of Alzheimer's disease and dementia

Although the information on this page concerns the L-carnitine form, we will still give its twin brother Acetyl-L-Carnitine credit as an experimental agent for delaying and preventing Alzheimer's disease.

In this disease, plaques and degenerative proteins accumulate in the neurons, including the cholinergic neurons, which are responsible for memory and memorization processes.

In Alzheimer's, as well as dementia, acetylcholine levels are low, and taking ALCAR can help keep them at more optimal levels, thus slowing the progression of the disease.

Benefits of taking L-carnitine in cardiovascular diseases

A number of studies have demonstrated encouraging results regarding the addition of L-carnitine as a dietary supplement in overweight people. In these cases, a reduction in diastolic arterial pressure is observed.

It also improves heart muscle function and reduces symptoms in patients suffering from congestive heart failure.

L-carnitine reduces bad cholesterol levels while simultaneously optimizing good HDL cholesterol levels, thus reducing the risk of atherosclerosis.

The antioxidant effect of carnitine is known. This property prevents the oxidation of lipoproteins and, accordingly, the deposition of plaques on the vessels.

L-carnitine improves sports performance

L-carnitine is a substance useful for the body, which performs a number of beneficial actions. However, he is best known in the field of sports. Its use is believed to produce a number of beneficial effects.

It should be taken into account that many of them occur after its longer use, and a large part are indirect as a result of its action at the cellular level.

This distinguishes it from other supplements that work instantly, but it does not mean that L-carnitine does not work and does not lead to beneficial effects.

L-carnitine has various beneficial effects related to sports:

• Helps to recover faster after physical exertion.
• Improves oxygen delivery to muscles. In this way, they become more durable during prolonged aerobic loads.
• Increases blood supply and nitric oxide production. It slows down the accumulation of lactic acid and slows down the feeling of fatigue.
• It is associated with increased erythrocyte synthesis in exercising individuals.
• Taken an hour before training, improves results and performance, both in the aerobic and anaerobic phases of training.

Benefits of L-carnitine in the fight against diabetes

Clinical studies have shown promising results on the role of carnitine in the control of type 2 diabetes.

Evidence suggests that its intake can reduce fasting blood glucose levels as well as glycated hemoglobin levels. At the same time, it improves insulin sensitivity in people with diabetes and obesity.

According to the study authors, the mechanism of action by which carnitine exerts its effects is that it modulates insulin receptors and changes the expression of specific genes responsible for blood sugar regulation.

It is hypothesized that this amino acid may improve pancreatic beta cell function. They are responsible for the production of insulin.

Benefits of L-carnitine as an antioxidant and protector for the liver

This makes it suitable in the fight against oxidative stress, as well as an assistant in carrying out detoxification processes in the body.

Research shows that taking L-carnitine as a supplement:

• Lowers liver enzyme levels
• Improves liver function
• It reduces the content of triglycerides.

It is suitable for people with impaired liver function, as well as for steatosis (fatty liver).

Benefits of L-Carnitine for Enhancing Fertility

Studies reveal that the intake of L-carnitine (3-5 g) per day leads to a significant increase in spermatogenesis, increases the quantity and quality of seminal fluid. It improves the motility and also the morphology of the spermatozoa.

In addition to male fertility, there is evidence that taking L-carnitine improves ovulation and increases conception rates in women with polycystic ovaries.

Benefits of L-carnitine in the treatment of chronic inflammatory diseases

According to some studies, L-carnitine reduces C-reactive protein levels. It is a biomarker for the level of systemic inflammation in the body.

Carnitine intake also reduces levels of malondialdehyde, a product of lipid oxidation. It is a pro-inflammatory biomarker responsible for the onset of pain syndrome in people suffering from osteoarthritis.

These results are encouraging and point to new studies on the possible role of L-carnitine in reducing inflammation and pain syndrome in people with chronic inflammatory and degenerative diseases of the bone and joint system.

What are the benefits of L-carnitine from VitaOn?

VitaOn provides you with high-quality, easily digestible L-carnitine in the form of L-carnitine tartrate.

Taking it will fill the necessary L-carnitine needs of your body to be able to perform smoothly all the functions and processes in which this substance is involved.

L-carnitine is a health supplement that has a variety of effects on human health. Its reception can benefit not only athletes, as was preached until recently, but all people who care about their health.

Frequently Asked Questions

Is there any benefit to taking L-carnitine in vegetarians?

Yes. Since L-carnitine is naturally found primarily in meat, adding it to the diet of vegetarians and vegans in the form of a dietary supplement can have a highly beneficial and noticeable effect.

Can body weight be reduced when taking L-carnitine if we are not in a caloric deficit?

No. Weight reduction is always and necessarily related to maintaining a negative caloric balance. L-carnitine can optimize the process under the condition of taking in fewer calories than burned.

Who Should Not Take L-Carnitine?

Children, pregnant and lactating women should not use the supplement due to insufficient information on its safety. Consult a doctor in case of taking medications that slow blood clotting.